inspectedthebody,andthenightafterattendedalady,Mrs。B。,whosickened,anddied16th。The10th,Iattendedanother,Mrs。G。,whosickened,butrecovered。March16th,IwentfromMrs。G。’sroomtoattendaMrs。H。,whosickened,anddied21st。The17th,IinspectedMrs。B。Onthe19th,IwentdirectlyfromMrs。H。’sroomtoattendanotherlady,Mrs。G。,whoalsosickened,anddied22d。WhileMrs。
  B。wassick,on15th,Iwentdirectlyfromherroomafewrods,andattendedanotherwoman,whowasnotsick。Upto20thofthismonthI
  worethesameclothes。Inowrefusedtoattendanylabor,anddidnottillApril21st,when,havingthoroughlycleansedmyself,I
  resumedmypractice,andhadnomorepuerperalfever。
  “Thecaseswerenotconfinedtoanarrowspace。Thetwonearestwerehalfamilefromeachother,andhalfthatdistancefrommyresidence。Theotherswerefromtwotothreemilesapart,andnearlythatdistancefrommyresidence。Therewerenoothercasesintheirimmediatevicinitywhichcametomyknowledge。Thegeneralhealthofallthewomenwasprettygood,andallthelaborsasgoodascommon,exceptthefirst。Thiswoman,inconsequenceofmynotarrivinginseason,andthechildbeinghalf-bornatsometimebeforeIarrived,wasverymuchexposedtothecoldatthetimeofconfinement,andafterwards,beingconfinedinaveryopen,coldroom。Ofthesixcasesyouperceiveonlyonerecovered。
  “Inthewinterof1817twoofmypatientshadpuerperalfever,oneverybadly,theothernotsobadly。Bothrecovered。Oneotherhadswelledleg,orphlegmasiadolens,andoneortwoothersdidnotrecoveraswellasusual。
  “Inthesummerof1835anotherdisastrousperiodoccurredinmypractice。July1st,Iattendedaladyinlabor,whowasafterwardsquiteillandfeverish;butatthetimeIdidnotconsiderhercaseadecidedpuerperalfever。Onthe8th,Iattendedonewhodidwell。
  Onthe12th,onewhowasseriouslysick。Thiswasalsoanequivocalcase,apparentlyarisingfromconstipationandirritationoftherectum。Thesewomenweretenmilesapartandfivefrommyresidence。
  On15thand20th,twowhodidwell。On25th,Iattendedanother。
  Thiswasaseverelabor,andfollowedbyunequivocalpuerperalfever,orperitonitis。Sherecovered。August2dand3d,inabouttwenty-
  fourhoursIattendedfourpersons。Twoofthemdidverywell;onewasattackedwithsomeofthecommonsymptoms,whichhoweversubsidedinadayortwo,andtheotherhaddecidedpuerperalfever,butrecovered。Thiswomanresidedfivemilesfromme。UptothistimeI
  worethesamecoat。Allmyotherclotheshadfrequentlybeenchanged。On6th,Iattendedtwowomen,oneofwhomwasnotsickatall;buttheother,Mrs。L。,wasafterwardstakenill。On10th,I
  attendedalady,whodidverywell。Ihadpreviouslychangedallmyclothes,andhadnogarmentonwhichhadbeeninapuerperalroom。
  On12th,IwascalledtoMrs。S。,inlabor。Whileshewasill,I
  lefthertovisitMrs。L。,oneoftheladieswhowasconfinedon6th。
  Mrs。L。hadbeenmoreunwellthanusual,butIhadnotconsideredhercaseanythingmorethancommontillthisvisit。Ihadonasurtoutatthisvisit,which,onmyreturntoMrs。S。,Ileftinanotherroom。Mrs。S。wasdeliveredon13thwithforceps。Thesewomenbothdiedofdecidedpuerperalfever。
  “WhileIattendedthesewomenintheirfevers,Ichangedmyclothes,andwashedmyhandsinasolutionofchlorideoflimeaftereachvisit。Iattendedsevenwomeninlaborduringthisperiod,allofwhomrecoveredwithoutsickness。
  “InmypracticeIhavehadseveralsinglecasesofpuerperalfever,someofwhomhavediedandsomehaverecovered。Untiltheyear1830
  Ihadnosuspicionthatthediseasecouldbecommunicatedfromonepatienttoanotherbyanurseormidwife;butInowthinktheforegoingfactsstronglyfavorthatidea。Iwassomuchconvincedofthisfact,thatIadoptedtheplanbeforerelated。
  “Ibelievemyownhealthwasasgoodasusualateachoftheaboveperiods。Ihavenorecollectionstothecontrary。
  “IbelieveIhaveansweredallyourquestions。Ihavebeenmoreparticularonsomepointsperhapsthannecessary;butIthoughtyoucouldformyourownopinionbetterthantotakemine。In1830I
  wrotetoDr。Charmingamoreparticularstatementofmycases。IfI
  havenotansweredyourquestionssufficiently,perhapsDr。C。mayhavemylettertohim,andyoucanfindyouranswerthere。“[Inalettertomyself,thisgentlemanalsostated,“Idonotrecollectthattherewasanyerysipelasoranyotherdiseaseparticularlyprevalentatthetime。“]
  “BOSTON,February3,1843。
  III。“MYDEARSIR,——Ireceivedanotefromyoulastevening,requestingmetoanswercertainquestionsthereinproposed,touchingthecasesofpuerperalfeverwhichcameundermyobservationthepastsummer。Itgivesmepleasuretocomplywithyourrequest,sofarasitisinmypowersotodo,but,owingtothehurryinpreparingforajourney,thenotesofthecasesIhadthentakenwerelostormislaid。Theprincipalfacts,however,aretoovividuponmyrecollectiontobesoonforgotten。Ithink,therefore,thatIshallbeabletogiveyoualltheinformationyoumayrequire。
  “Allthecasesthatoccurredinmypracticetookplacebetweenthe7thofMayandthe17thofJune1842。
  “Theywerenotconfinedtoanyparticularpartofthecity。ThefirsttwocaseswerepatientsresidingattheSouthEnd,thenextwasattheextremeNorthEnd,onelivinginSeaStreetandtheotherinRoxbury。Thefollowingistheorderinwhichtheyoccurred:
  “Case1。Mrs。_____wasconfinedonthe7thofMay,at5o’clock,P。M。,afteranaturallaborofsixhours。At12o’clockatnight,onthe9ththirty-onehoursafterconfinement,shewastakenwithseverechill,previoustowhichshewasascomfortableaswomenusuallyareunderthecircumstances。Shediedonthe10th。
  “Case2。Mrs。_____wasconfinedonthe10thofJunefourweeksafterMrs。C。,at11A。M。,afteranatural,butsomewhatseverelaboroffivehours。At7o’clock,onthemorningofthe11th,shehadachill。Diedonthe12th。
  “Case3。Mrs。_____,confinedonthe14thofJune,wascomfortableuntilthe18th,whensymptomsofpuerperalfeverweremanifest。Shediedonthe20th。
  “Case4。Mrs。_____,confinedJune17th,at5o’clock,A。M。,wasdoingwelluntilthemorningofthe19th。Shediedontheeveningofthe21st。
  “Case5。Mrs。_____wasconfinedwithherfifthchildonthe17thofJune,at6o’clockintheevening。Thispatienthadbeenattackedwithpuerperalfever,atthreeofherpreviousconfinements,butthediseaseyieldedtodepletionandotherremedieswithoutdifficulty。
  Thistime,Iregrettosay,Iwasnotsofortunate。Shewasnotattacked,asweretheotherpatients,withachill,butcomplainedofextremepaininabdomen,andtendernessonpressure,almostfromthemomentofherconfinement。Inthisasintheothercases,thediseaseresistedallremedies,andshediedingreatdistressonthe22dofthesamemonth。Owingtotheextremeheatoftheseason,andmyownindisposition,noneofthesubjectswereexaminedafterdeath。
  Dr。Channing,whowasinattendancewithmeonthethreelastcases,proposedtohaveapost-mortemexaminationofthesubjectofcaseNo。
  5,butfromsomecausewhichIdonotnowrecollectitwasnotobtained。
  “YouwishtoknowwhetherIworethesameclotheswhenattendingthedifferentcases。Icannotpositivelysay,butIshouldthinkIdidnot,astheweatherbecamewarmerafterthefirsttwocases;I
  thereforethinkitprobablethatImadeachangeofatleastapartofmydress。Ihavehadnoothercaseofpuerperalfeverinmyownpracticeforthreeyears,savethoseaboverelated,andIdonotremembertohavelostapatientbeforewiththisdisease。Whileabsent,lastJuly,Ivisitedtwopatientssickwithpuerperalfever,withafriendofmineinthecountry。Bothofthemrecovered。
  “ThecasesthatIhaverecordedwerenotconfinedtoanyparticularconstitutionortemperament,butitseizeduponthestrongandtheweak,theoldandtheyoung,——onebeingoverfortyyears,andtheyoungestundereighteenyearsofage……Ifthediseaseisofanerysipelatousnature,asmanysuppose,contagionistsmayperhapsfindsomegroundfortheirbeliefinthefact,that,fortwoweeksprevioustomyfirstcaseofpuerperalfever,Ihadbeenattendingaseverecaseoferysipelas,andtheinfectionmayhavebeenconveyedthroughmetothepatient;but,ontheotherhand,whyisnotthisthecasewithotherphysicians,orwiththesamephysicianatalltimes,forsincemyreturnfromthecountryIhavehadamoreinveteratecaseoferysipelasthaneverbefore,andnodifficultywhateverhasattendedanyofmymidwiferycases?“
  Iamassured,onunquestionableauthority,that“Aboutthreeyearssince,agentlemaninextensivemidwiferybusiness,inaneighboringState,lostinthecourseofafewweekseightpatientsinchild-bed,sevenofthembeingundoubtedcasesofpuerperalfever。Nootherphysicianofthetownlostasinglepatientofthisdiseaseduringthesameperiod。“AndfromwhatIhaveheardinconversationwithsomeofourmostexperiencedpractitioners,Iaminclinedtothinkmanycasesofthekindmightbebroughttolightbyextensiveinquiry。
  Thislongcatalogueofmelancholyhistoriesassumesastilldarkeraspectwhenwerememberhowkindlynaturedealswiththeparturientfemale,whensheisnotimmersedinthevirulentatmosphereofanimpurelying-inhospital,orpoisonedinherchamberbytheunsuspectedbreathofcontagion。Fromallcausestogether,notmorethanfourdeathsinathousandbirthsandmiscarriageshappenedinEnglandandWalesduringtheperiodembracedbythefirstReportoftheRegistrar-General。“InthesecondReportthemortalitywasshowntobeaboutfiveinonethousand。IntheDublinLying-inHospital,duringthesevenyearsofDr。Collins’smastership,therewasonecaseofpuerperalfeverto178deliveries,orlessthansixtothethousand,andonedeathfromthisdiseasein278cases,orbetweenthreeandfourtothethousandayetduringthisperiodthediseasewasendemicinthehospital,andmighthavegoneontorivalthehorrorsofthepestilenceoftheMaternite,hadnotthepoisonbeendestroyedbyathoroughpurification。
  Inprivatepractice,leavingoutofviewthecasesthataretobeascribedtotheself-actingsystemofpropagation,itwouldseemthatthediseasemustbefarfromcommon。Mr。WhiteofManchestersays,“Outofthewholenumberoflying-inpatientswhomIhavedeliveredandImaysafelycallitagreatone,Ihaveneverlostone,nortothebestofmyrecollectionhasonebeengreatlyendangered,bythepuerperal,miliary,lownervous,putridmalignant,ormilkfever。“
  Dr。JosephClarkeinformedDr。Collins,thatinthecourseofforty-
  fiveyears’mostextensivepracticehelostbutfourpatientsfromthisdisease。OneofthemosteminentpractitionersofGlasgow,whohasbeenengagedinveryextensivepracticeforupwardsofaquarterofacentury,testifiesthatheneversawmorethantwelvecasesofrealpuerperalfever。[Lancet,May4,1833]
  Ihavemyselfbeentoldbytwogentlemenpractisinginthiscity,andhavingformanyyearsalargemidwiferybusiness,thattheyhadneitherofthemlostapatientfromthisdisease,andbyoneofthemthathehadonlyseenitinconsultationwithotherphysicians。Infivehundredcasesofmidwifery,ofwhichDr。StorerhasgivenanabstractinthefirstnumberofthisJournal,therewasonlyoneinstanceoffatalpuerperalperitonitis。
  Intheviewofthesefacts,itdoesappearasingularcoincidence,thatonemanorwomanshouldhaveten,twenty,thirty,orseventycasesofthisrarediseasefollowinghisorherfootstepswiththekeennessofabeagle,throughthestreetsandlanesofacrowdedcity,whilethescoresthatcrossthesamepathsonthesameerrandsknowitonlybyname。Itisaseriesofsimilarcoincidenceswhichhasledustoconsiderthedagger,themusket,andcertaininnocent-
  lookingwhitepowdersashavingsomelittleclaimtoberegardedasdangerous。Itisthepracticalinattentiontosimilarcoincidenceswhichhasgivenrisetotheunpleasantbutoftennecessarydocumentscalledindictments,whichhassharpenedaformofthecephalotomesometimesemployedinthecaseofadults,andadjustedthatmodificationofthefilletwhichdeliverstheworldofthosewhohappentobetoomuchinthewaywhilesuchstrikingcoincidencesaretakingplace。
  Ishallnowmentionafewinstancesinwhichthediseaseappearstohavebeenconveyedbytheprocessofdirectinoculation。
  Dr。CampbellofEdinburghstatesthatinOctober,1821,heassistedatthepost-mortemexaminationofapatientwhodiedwithpuerperalfever。Hecarriedthepelvicviscerainhispockettotheclass-